Delamanid (OPC-67683)

Name: Delamanid (OPC-67683)
SKU: A12864
Price: 175 CNY
Rating: 5 (3 reviews)

目录号: A12864

Antibiotic

3 篇发表文献

Delamanid 是一种新型抗结核药物，它抑制肉豆蔻酸的合成，并且在体外和体内对耐药性结核分枝杆菌株表现出强大的活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥840.00	现货
50mg	¥1,540.00	现货
100mg	¥2,520.00	现货
500mg	¥5,950.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Delamanid (OPC-67683)发表的3篇文献

Thanh Quang Nguyen, .et al. , Antimicrob Agents Chemother, 2022, Dec 20;66(12):e0044822 PMID: 36321819

Meikle V, .et al. , Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480

World Health Organization, .et al. , World Health Organization, 2018, WHO/CDS/TB/2018.24

生物活性

Discription

Delamanid is a new antituberculosis drug that inhibits mycolic acid synthesis and has shown potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12864
分子式	C25H25F3N4O6
分子量	534.48
CAS号	681492-22-8
SMILES	C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	85 mg/mL (159.03 mM) Need ultrasonic
	Water	Insoluble
	Ethanol	2 mg/mL
In vivo	2.5 mg/mL (4.68 mM) Need ultrasonic	10% DMSO 40% PEG300 5% Tween-80 45% Saline
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.71 mL	93.55 mL	187.1 mL
0.5 mM	3.74 mL	18.71 mL	37.42 mL
1 mM	1.87 mL	9.35 mL	18.71 mL
5 mM	0.37 mL	1.87 mL	3.74 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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