Deltarasin HCl

Name: Deltarasin HCl
SKU: A13722

目录号: A13722

PDE-KRAS 抑制剂

Deltarasin HCl Chemical Structure

CAS NO. 1440898-82-7 (HCl), 1440898-61-2

Deltarasin HCl是一种新型的抑制KRASPDEδ相互作用从而破坏致癌性KRAS信号的小分子。

库存：现货

规格	价格	数量
5 mg	￥ 1,050.00
10 mg	￥ 1,470.00
25 mg	￥ 2,940.00
10mM * 1mL in DMSO	￥ 1,365.00

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产品详情

生物活性

Deltarasin HCl是一种新型的抑制KRASPDEδ相互作用从而破坏致癌性KRAS信号的小分子。

靶点信息

PDEδ
38 nM(Kd)

溶解度 *

In vitro	DMSO	89 mg/mL (147.41 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (147.41 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.02 mL	70.11 mL	140.22 mL
0.5 mM	2.8 mL	14.02 mL	28.04 mL
1 mM	1.4 mL	7.01 mL	14.02 mL
5 mM	0.28 mL	1.4 mL	2.8 mL

*The above data is based on the productmolecular weight 713.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13722
作用机制	Inhibitor (抑制剂)
M. Wt	713.14
Formula	C40H37N5O.3HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1440898-82-7 (HCl), 1440898-61-2
SMILES	C1CNCCC1[C@@H](COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8.Cl.Cl.Cl