Deltarasin HCl
目录号: A13722
PDE-KRAS 抑制剂
Deltarasin 是一种新型小分子,它通过抑制 KRAS PDEδ 之间的相互作用,从而阻断致癌的 KRAS 信号传导。
Discription | Deltarasin is a novel small molecule inhibiting the KRAS PDEδ interaction and thus impairing oncogenic KRAS signalling. | ||
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Targets |
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目录号 | A13722 |
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分子式 | C40H37N5O.3HCl |
分子量 | 713.14 |
CAS号 | 1440898-82-7 (HCl), 1440898-61-2 |
SMILES | C1CNCCC1[C@@H](COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8.Cl.Cl.Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 89 mg/mL (147.41 mM) | |
Water | Insoluble | ||
Ethanol | 89 mg/mL (147.41 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 14.02 mL | 70.11 mL | 140.22 mL |
0.5 mM | 2.8 mL | 14.02 mL | 28.04 mL |
1 mM | 1.4 mL | 7.01 mL | 14.02 mL |
5 mM | 0.28 mL | 1.4 mL | 2.8 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2