目录号: A13063
FASN inhibitor
Denifanstat(TVB-2640)是一种从专利 WO2012122391A1 中提取的脂肪酸合成酶(FASN)抑制剂,化合物152,具有 0.052 μM 的 IC50 和 0.072 μM 的 EC50。
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生物活性
Discription | Denifanstat (TVB-2640) is a Fatty Acid Synthase (FASN) inhibitor extracted from patent WO2012122391A1, compound 152, has an IC50 of 0.052 μM and an EC50 of 0.072 μM. |
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产品信息
目录号 | A13063 |
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分子式 | C27H29N5O |
分子量 | 439.55 |
CAS号 | 1399177-37-7 |
SMILES | N#CC1=CC=C(C2CCN(C(C3=CC(C4=NC(C)=NN4)=C(C5CCC5)C=C3C)=O)CC2)C=C1 |
其他名称 | FASN-IN-2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro | DMSO | 79 mg/mL (179.73 mM) | |
Water | Insoluble | ||
Ethanol | 79 mg/mL (179.73 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.75 mL | 113.75 mL | 227.51 mL |
0.5 mM | 4.55 mL | 22.75 mL | 45.5 mL |
1 mM | 2.28 mL | 11.38 mL | 22.75 mL |
5 mM | 0.46 mL | 2.28 mL | 4.55 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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