Desmethyl-QCA276

Name: Desmethyl-QCA276
SKU: A20648
Price: 2240 CNY
Rating: 5 (288 reviews)

目录号: A20648

Desmethyl-QCA276，一种基于QCA276的基团，通过连接体与cereblon配体结合，形成PROTAC以降解BET。QCA276是一种BET抑制剂，其IC50为10 nM，Ki为2.3 nM。

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1mg	¥2,240.00	现货
5mg	¥6,720.00	现货
10mg	¥11,200.00	现货
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Data Sheet

SDS

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生物活性

Discription	Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM.

产品信息

目录号	A20648
分子式	C21H17N5OS
分子量	387.46
CAS号	2126819-55-2
SMILES	CC1=NN=C2COCC(C(CC3=CC=CC=C3)=C(C#CC4=CNN=C4)S5)=C5N21
其他名称	PROTAC BRD4-binding moiety 4
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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