Diclofenac sodium
目录号: A10304
COX 抑制剂
Diclofenac Sodium 是一种非选择性 COX 抑制剂,其 IC50 分别为 0.5 μg/ml 对 COX-1 和 COX-2 在完整细胞中,被用作非甾体抗炎药(NSAID),用于缓解疼痛和减少炎症肿胀。
Discription | Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation. | ||
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目录号 | A10304 |
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分子式 | C14H10Cl2NNaO2 |
分子量 | 318.13 |
CAS号 | 15307-79-6 |
SMILES | C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+] |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 54 mg/mL (169.74 mM) | |
Water | 12 mg/mL (37.71 mM) | ||
Ethanol | 54 mg/mL (169.74 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 31.43 mL | 157.17 mL | 314.34 mL |
0.5 mM | 6.29 mL | 31.43 mL | 62.87 mL |
1 mM | 3.14 mL | 15.72 mL | 31.43 mL |
5 mM | 0.63 mL | 3.14 mL | 6.29 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2