DMH-1

Name: DMH-1
SKU: A12820

目录号: A12820

ALK2 抑制剂

Product Citations (1)

DMH-1 Chemical Structure

CAS NO. 1206711-16-1

DMH-1是骨形态发生蛋白（BMP）ALK2受体的选择性抑制剂（IC50 = 108 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 560.00
25 mg	￥ 1,050.00
50 mg	￥ 1,610.00
100 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 623.00

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生物活性

DMH-1是骨形态发生蛋白（BMP）ALK2受体的选择性抑制剂（IC50 = 108 nM）。

靶点信息

ALK2
107.9 nM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 21 mg/mL (55.19 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+35% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.29 mL	131.43 mL	262.85 mL
0.5 mM	5.26 mL	26.29 mL	52.57 mL
1 mM	2.63 mL	13.14 mL	26.29 mL
5 mM	0.53 mL	2.63 mL	5.26 mL

*The above data is based on the productmolecular weight 380.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12820
作用机制	Inhibitor (抑制剂)
M. Wt	380.44
Formula	C24H20N4O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1206711-16-1
Synonyms	DMH1
SMILES	CC(C)OC1=CC=C(C=C1)C2=CN3C(=C(C=N3)C4=CC=NC5=CC=CC=C45)N=C2