DMX-5804

Name: DMX-5804
SKU: A20199
Price: 700 CNY
Rating: 5 (288 reviews)

目录号: A20199

MAP4K4 抑制剂

DMX-5804 是一种强效的、口服活性的、选择性的 MAP4K4 抑制剂，具有 3 nM 的 IC50 和 8.55 的 pIC50，针对人类 MAP4K4。对 MINK1/MAP4K6 的抑制作用较弱（pIC50 为 8.18），对 TNIK/MAP4K7 的抑制作用也较弱（pIC50 为 7.96）。

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Grouped product items
规格	价格	库存
1mg	¥700.00	现货
2mg	¥1,050.00	现货
5mg	¥1,680.00	现货
10mg	¥2,730.00	现货
25mg	¥4,585.00	现货
50mg	¥6,580.00	现货
100mg	¥8,925.00	现货
*10mM 1mL in DMSO**	¥1,855.00	现货
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Data Sheet

SDS

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生物活性

Discription

DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96).

Targets

Target	Value

产品信息

目录号	A20199
分子式	C21H19N3O3
分子量	361.39
CAS号	2306178-56-1
SMILES	O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4
其他名称	DMX5804, DMX 5804
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	71 mg/mL (196.46 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (2.77 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.67 mL	138.35 mL	276.71 mL
0.5 mM	5.53 mL	27.67 mL	55.34 mL
1 mM	2.77 mL	13.84 mL	27.67 mL
5 mM	0.55 mL	2.77 mL	5.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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