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DMXAA (ASA404, Vadimezan)

DMXAA (ASA404, Vadimezan)

Name: DMXAA (ASA404, Vadimezan)
SKU: A10324

目录号: A10324

Vascular Disrupting Agent (VDA)

Product Citations (3)

DMXAA (ASA404, Vadimezan) Chemical Structure

CAS NO. 117570-53-3

DMXAA (ASA404,Vadimezan)是一种肿瘤血管破坏剂（tumor-VDA），也是一种DT-diaphorase的竞争性抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
25 mg	￥ 1,820.00
50 mg	￥ 3,150.00
100 mg	￥ 4,900.00
10mM * 1mL in DMSO	￥ 728.00

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生物活性

DMXAA (ASA404,Vadimezan)是一种肿瘤血管破坏剂（tumor-VDA），也是一种DT-diaphorase的竞争性抑制剂。

靶点信息

DT-diaphorase (Cell-free assay)	DT-diaphorase (Cell-free assay)
20 μM(Ki)	20 μM(Ki)

溶解度 *

In vitro	DMSO	7 mg/mL (24.79 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.42 mL	177.12 mL	354.23 mL
0.5 mM	7.08 mL	35.42 mL	70.85 mL
1 mM	3.54 mL	17.71 mL	35.42 mL
5 mM	0.71 mL	3.54 mL	7.08 mL

*The above data is based on the productmolecular weight 282.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10324
M. Wt	282.3
Formula	C17H14O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	117570-53-3
Synonyms	AS-1404, 5,6-MeXAA, NSC-640488, Vadimezan
SMILES	CC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C