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NU6027
Catalog No. A14136 -
Nedisertib
Catalog No. A17055 DNA-PK 抑制剂Nedisertib (M-3814,MSC2490484A)是一种可口服的DNA依赖性蛋白激酶（DNA-PK）抑制剂，具有潜在的抗肿瘤和化学/放射增敏活性。 了解更多 -
(Rac)-Nedisertib
Catalog No. A21383 DNA-PK inhibitor(Rac)-Nedisertib ((Rac)-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of <3 nM. 了解更多 -
Compound 401
Catalog No. A11778 DNA-PK 抑制剂Compound 401是一种细胞可渗透的嘧啶-异喹啉酮化合物，可作为有效的，可逆的和ATP竞争的DNA-PK抑制剂（IC50 = 280 nM），选择性是mTOR（IC50 = 5.3μM）的19倍。 了解更多 -
KU 0060648
Catalog No. A13224 DNA-PK 抑制剂KU0060648是一种有效且选择性的DNA依赖性蛋白激酶（DNA-PK）抑制剂（IC50 = 8.6 nM）；对DNA-PK的选择性是其他PIKK的20-1000倍，并且有60种激酶。KU-0060648可提高HDR效率并衰减NHEJ频率。 了解更多 -
ETP-46464
Catalog No. A13328 -
CC-115
Catalog No. A15779 -
PIK-75 hydrochloride
Catalog No. A10729 PI3K 抑制剂PIK-75是一种p110α抑制剂，IC50值为5.8nM。在p110γ和p110β的效果较差，IC50值为0.076 ?M和1.3 ?M。 了解更多 -
NU-7441 (KU-57788)
Catalog No. A11098 DNA-PK 抑制剂NU-7441 (KU-57788)是一种有效的选择性DNA依赖性蛋白激酶（DNA-PK）抑制剂。对于DNA-PK，mTOR，PI 3-K，ATM和ATR，IC50值分别为14、1700、5000，> 100000和> 100000 nM。 了解更多 -
Pamiparib
Catalog No. A17073 -
Rucaparib (Camsylate)
Catalog No. A18013 PARP 抑制剂Rucaparib Camsylate is an inhibitor of PARP with a Ki of 1.4 nM for PARP1, and also shows binding affinity to eight other PARP domains. 了解更多 -
PARP14 inhibitor H10
Catalog No. A18616 PARP14 抑制剂PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (??24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis. 了解更多 -
Niraparib tosylate
Catalog No. A16618 PARP1/PARP2 inhibitorNiraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. 了解更多 -
Niraparib hydrochloride
Catalog No. A18018 PARP1 and PARP2 inhibitorNiraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多 -
Niraparib R-enantiomer
Catalog No. A21880 PARP1 inhibitorNiraparib R-enantiomer (MK-4827 R-enantiomer) is an excellent PARP1 inhibitor with IC50 of 2.4 nM. 了解更多 -
Veliparib dihydrochloride
Catalog No. A21356 PARP inhibitorVeliparib dihydrochloride is a potent PARP inhibitor, inhibiting PARP1 and PARP2 with Kis of 5.2 and 2.9 nM, respectively. 了解更多 -
AZD-2461
Catalog No. A12393 -
ME0328
Catalog No. A14309 -
Benzamide
Catalog No. A14371 -
BMN-673 8R,9S
Catalog No. A15024 -
4-HQN
Catalog No. A15370 -
BYK 204165
Catalog No. A15371 -
DR 2313
Catalog No. A15373 -
NU 1025
Catalog No. A15375 -
NVP-TNKS656
Catalog No. A15786 -
Talazoparib tosylate
Catalog No. A20238 PARP1/2 inhibitorTalazoparib tosylate (BMN 673ts) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1. 了解更多
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