DNA
目录号
产品名
应用
产品描述
文献引用
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Protein Synthesis Inhibitor
环己酰胺(又称为放线菌酮)被用作一种选择性抗生素。它通过与80S核糖体结合,抑制腐生真菌真核生物的蛋白质合成(依赖DNA的RNA),而对皮肤癣菌和系统性真菌无效。- Tianfeng Huang, .et al. , Mol Neurobiol, 2024, Sep 13 PMID: 39271624
- Han Xiao, .et al. , JPA, 2023, Apr 19
- Shuanghui Lu, .et al. , Chem Biol Interact, 2022, Dec 1;368:110219 PMID: 36243147
- Ke Chen, .et al. , Cancer Commun (Lond), 2021, Apr; 41(4): 316-332 PMID: 33591636
- Zhiyuan Qin, .et al. , Cancers (Basel), 2021, Feb 4;13(4):618 PMID: 33557163
- Hua Xu, .et al. , Cancers (Basel), 2020, Apr; 12(4): 831 PMID: 32235588
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DNA and RNA synthesis inhibitor
氟尿嘧啶(Adrucil)是一种自杀抑制剂,其作用机制是通过不可逆地抑制胸苷酸合成酶来发挥作用。- Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591
- Adi Jacob Berger, .et al. , Nat Cancer, 2021, 2, 1055-1070 PMID: 35121883