Docetaxel (Taxotere)

Name: Docetaxel (Taxotere)
SKU: A10326

目录号: A10326

Microtubule Associated 抑制剂

Docetaxel (Taxotere) Chemical Structure

CAS NO. 114977-28-5

Docetaxel (Taxotere)多西他赛一种taxol类似物，是一种microtubules解聚抑制剂，通过结合于稳定的微管发挥作用。

库存：现货

规格	价格	数量
10 mg	￥ 210.00
50 mg	￥ 350.00
100 mg	￥ 420.00
200 mg	￥ 595.00
10mM * 1mL in DMSO	￥ 350.00

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生物活性

Docetaxel (Taxotere)多西他赛一种taxol类似物，是一种microtubules解聚抑制剂，通过结合于稳定的微管发挥作用。

靶点信息

Microtubules (Cell-free assay)

溶解度 *

In vitro (25°C)	DMSO	92 mg/mL (113.88 mM)
	Water	Insoluble
	Ethanol	Warmed: 49 mg/mL (60.65 mM)
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.38 mL	61.89 mL	123.78 mL
0.5 mM	2.48 mL	12.38 mL	24.76 mL
1 mM	1.24 mL	6.19 mL	12.38 mL
5 mM	0.25 mL	1.24 mL	2.48 mL

*The above data is based on the productmolecular weight 807.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10326
作用机制	Inhibitor (抑制剂)
M. Wt	807.9
Formula	C43H53NO14
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	114977-28-5
Synonyms	Taxotere
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O