Dorsomorphin 2HCl

Name: Dorsomorphin 2HCl
SKU: A13720
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A13720

BMP 抑制剂

1 篇发表文献

Dorsomorphin，也被称为 BML-275，是一种选择性的小分子抑制剂，用于抑制 BMP信号传导，它在胚胎干细胞中促进心脏发生。Dorsomorphin 通过抑制骨形态发生蛋白信号传导，逆转乳腺癌起始细胞的间充质表型。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥280.00	现货
10mg	¥525.00	现货
25mg	¥1,050.00	现货
50mg	¥1,680.00	现货
100mg	¥3,080.00	现货
500mg	¥6,860.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Dorsomorphin 2HCl发表的1篇文献

Kameshima S, .et al. , Apoptosis, 2019, Feb 8 PMID: 30737648

生物活性

Discription

Dorsomorphin, also known as BML-275, is a selective small molecule inhibitor of BMP signaling, which promotes cardiomyogenesis in embryonic stem cells. Dorsomorphin reverses the mesenchymal phenotype of breast cancer initiating cells by inhibition of bone morphogenetic protein signaling.

Targets

Target	Value

产品信息

目录号	A13720
分子式	C24H27Cl2N5O
分子量	472.41
CAS号	1219168-18-9
SMILES	C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl
其他名称	Compound C, BML-275, BML275, BML 275
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Insoluble
	Water	87 mg/mL (184.15 mM)
	Ethanol	Insoluble
In vivo	PBS	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.17 mL	105.84 mL	211.68 mL
0.5 mM	4.23 mL	21.17 mL	42.34 mL
1 mM	2.12 mL	10.58 mL	21.17 mL
5 mM	0.42 mL	2.12 mL	4.23 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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