Dorsomorphin 2HCl

Name: Dorsomorphin 2HCl
SKU: A13720

目录号: A13720

BMP 抑制剂

Product Citations (1)

Dorsomorphin 2HCl Chemical Structure

CAS NO. 1219168-18-9

Dorsomorphin 2HCl (BML-275)是BMP信号传导的选择性小分子抑制剂，可促进胚胎干细胞的心肌发生。Dorsomorphin通过抑制骨形态发生蛋白信号转导逆转乳腺癌起始细胞的间质表型。

库存：现货

规格	价格	数量
10 mg	￥ 525.00
25 mg	￥ 1,050.00
50 mg	￥ 1,750.00
10mM * 1mL in DMSO	￥ 385.00

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生物活性

靶点信息

AMPK (Cell-free assay)
109 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	Insoluble
	Water	87 mg/mL (184.15 mM)
	Ethanol	Insoluble
In vivo	PBS	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.17 mL	105.84 mL	211.68 mL
0.5 mM	4.23 mL	21.17 mL	42.34 mL
1 mM	2.12 mL	10.58 mL	21.17 mL
5 mM	0.42 mL	2.12 mL	4.23 mL

*The above data is based on the productmolecular weight 472.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13720
作用机制	Inhibitor (抑制剂)
M. Wt	472.41
Formula	C24H27Cl2N5O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1219168-18-9
Synonyms	Compound C, BML-275, BML275, BML 275
SMILES	C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl