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Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.6 mL | 108.01 mL | 216.02 mL |
| 0.5 mM | 4.32 mL | 21.6 mL | 43.2 mL |
| 1 mM | 2.16 mL | 10.8 mL | 21.6 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.32 mL |
*The above data is based on the productmolecular weight 462.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22297 |
|---|---|
| M. Wt | 462.93 |
| Formula | C22H27ClN4O5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1191995-00-2 |
| Synonyms | HMS5552 |
| SMILES | O=C(NC1=NN(C[C@@H](O)CO)C=C1)[C@@H](N2CC(OC(C=CC=C3)=C3Cl)=CC2=O)CC(C)C |
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