Dorzolamide HCL

Name: Dorzolamide HCL
SKU: A10333

目录号: A10333

carbonic anhydrase 抑制剂

Dorzolamide HCL Chemical Structure

CAS NO. 130693-82-2

Dorzolamide HCl是一种碳酸酐酶抑制剂。它是一种抗青光眼剂，以滴眼剂的形式局部使用。盐酸度尔佐胺用于降低开角型青光眼和高眼压患者的眼内压升高。

库存：现货

规格	价格	数量
10 mg	￥ 420.00
50 mg	￥ 700.00
100 mg	￥ 1,050.00

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生物活性

靶点信息

Carbonic anhydrase II	Carbonic anhydrase IV	Carbonic anhydrase I
1.9 nM(Ki)	31 nM(Ki)	6000 nM(Ki)

溶解度 *

In vitro	DMSO	Insoluble
	Water	12 mg/mL (33.25 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.71 mL	138.54 mL	277.09 mL
0.5 mM	5.54 mL	27.71 mL	55.42 mL
1 mM	2.77 mL	13.85 mL	27.71 mL
5 mM	0.55 mL	2.77 mL	5.54 mL

*The above data is based on the productmolecular weight 360.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10333
作用机制	Inhibitor (抑制剂)
M. Wt	360.9
Formula	C10H17ClN2O4S3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	130693-82-2
Synonyms	Trusopt, Cosopt
SMILES	CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl