Dovitinib (TKI-258)

Name: Dovitinib (TKI-258)
SKU: A11411
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A11411

RTK 抑制剂

1 篇发表文献

Dovitinib 是一种小分子多靶点受体酪氨酸激酶抑制剂，它能够抑制通过 ZNF198-FGFR1 或 BCR-FGFR1 转化为 IL3 独立的 Ba/F3 细胞，其 IC50 值分别为 150 nM 和 90 nM。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥840.00	现货
50mg	¥1,400.00	现货
100mg	¥2,275.00	现货
200mg	¥3,570.00	现货
500mg	¥5,740.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Dovitinib (TKI-258)发表的1篇文献

Yunping Hu, .et al. , Cancer Lett, 2022, Oct 28;547:215867 PMID: 35985510

生物活性

Discription

Dovitinib is a small-molecule multitargeted receptor tyrosine kinase inhibitor, which inhibits Ba/F3 cells transformed to IL3 independence by ZNF198-FGFR1 or BCR-FGFR1 with IC50 values of 150 nM and 90 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11411
分子式	C21H21FN6O
分子量	392.4
CAS号	405169-16-6
SMILES	CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C\4/C(=C5C(=NC4=O)C=CC=C5F)N)/N3
其他名称	CHIR-258, CHIR258, TKI258
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	28 mg/mL (71.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.48 mL	127.42 mL	254.84 mL
0.5 mM	5.1 mL	25.48 mL	50.97 mL
1 mM	2.55 mL	12.74 mL	25.48 mL
5 mM	0.51 mL	2.55 mL	5.1 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 Dovitinib (TKI-258) | Dovitinib (TKI-258) 供应商 | Dovitinib (TKI-258) 花费 | Dovitinib (TKI-258) 生产商 | 订购 Dovitinib (TKI-258) | Dovitinib (TKI-258) 代理商 | 购买 405169-16-6 | 405169-16-6 供应商 | 405169-16-6 花费 | 405169-16-6 生产商 | 订购 405169-16-6 | 405169-16-6 代理商