Doxazosin

Name: Doxazosin
SKU: A17779

目录号: A17779

α-1 adrenergic receptor blocker

Doxazosin Chemical Structure

CAS NO. 74191-85-8

Doxazosin is an α-1 adrenergic receptor blocker that inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. Blockages of the alpha-1 adrenergic action on the vascular smooth muscles lead to a decrease in vascular resistance and antihypertensive activity.

库存：现货

规格	价格	数量
100 mg	￥ 420.00
500 mg	￥ 840.00

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生物活性

溶解度 *

In vitro	DMSO	29 mg/mL (64.23 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.15 mL	110.75 mL	221.49 mL
0.5 mM	4.43 mL	22.15 mL	44.3 mL
1 mM	2.21 mL	11.07 mL	22.15 mL
5 mM	0.44 mL	2.21 mL	4.43 mL

*The above data is based on the productmolecular weight 451.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17779
作用机制	Blocker (阻断剂)
M. Wt	451.48
Formula	C23H25N5O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	74191-85-8
Synonyms	Doxazosin; Cardura; 74191-85-8; Doxazosinum; Doxazosina; Doxazosine; Alfamedin; Aliud Brand of Doxazosin Mesylate; Almirall Brand of Doxazosin Mesylate; Alpharma Brand of Doxazosin Mesylate; Alter Brand of Doxazosin Mesylate; Apo Doxazosin; Apo-Doxazosin;
SMILES	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC