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DPPI 1c hydrochloride是一种双氰基吡咯烷化合物，可作为CD26（DPP 4）的缓慢结合和定点活性抑制剂，IC50 = 106 nM，对DPP II，DPP III，DPP VIII，DPP IX，FAP几乎没有活性，甚至浓度高达30μM的APP。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.97 mL | 159.85 mL | 319.69 mL |
| 0.5 mM | 6.39 mL | 31.97 mL | 63.94 mL |
| 1 mM | 3.2 mL | 15.98 mL | 31.97 mL |
| 5 mM | 0.64 mL | 3.2 mL | 6.39 mL |
*The above data is based on the productmolecular weight 312.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15298 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 312.8 |
| Formula | C14H20N4O2.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 866396-34-1 |
| Synonyms | Dipeptidylpeptidase IV Inhibitor III |
| SMILES | C1CCC(C1)(CO)NCC(=O)N2C(CCC2C#N)C#N.Cl |
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