Droxinostat

Name: Droxinostat
SKU: A10337
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A10337

HDAC 抑制剂

Droxinostat 是一种选择性的 HDAC3、HDAC6 和 HDAC8 抑制剂，对 HDAC6 和 HDAC8 的抑制作用相当，其半抑制浓度（IC50）分别为 2.47 和 1.46 微摩尔/升。

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥210.00	现货
25mg	¥455.00	现货
50mg	¥875.00	现货
100mg	¥1,435.00	现货
200mg	¥2,170.00	现货
*10mM 1mL in DMSO**	¥140.00	现货
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Data Sheet

SDS

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生物活性

Discription

Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 that shows comparable inhibition of HDAC6 and HDAC8 with IC50 = 2.47 and 1.46 μmol/L, respectively.

Targets

Target	Value

产品信息

目录号	A10337
分子式	C11H14ClNO3
分子量	243.7
CAS号	99873-43-5
SMILES	CC1=C(C=CC(=C1)Cl)OCCCC(=O)NO
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	47 mg/mL (192.86 mM)
	Water	Insoluble
	Ethanol	47 mg/mL (192.86 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	41.03 mL	205.17 mL	410.34 mL
0.5 mM	8.21 mL	41.03 mL	82.07 mL
1 mM	4.1 mL	20.52 mL	41.03 mL
5 mM	0.82 mL	4.1 mL	8.21 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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