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DT2216 is a potent and selective BCL-XL degrader based on PROTAC technology.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 6.48 mL | 32.42 mL | 64.84 mL |
| 0.5 mM | 1.3 mL | 6.48 mL | 12.97 mL |
| 1 mM | 0.65 mL | 3.24 mL | 6.48 mL |
| 5 mM | 0.13 mL | 0.65 mL | 1.3 mL |
*The above data is based on the productmolecular weight 1542.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22050 |
|---|---|
| M. Wt | 1542.36 |
| Formula | C77H96ClF3N10O10S4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 2365172-42-3 |
| SMILES | CC1(C)CCC(C2=CC=C(Cl)C=C2)=C(C1)CN3CCN(C4=CC=C(C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(N[C@@H](CSC6=CC=CC=C6)CCN7CCN(C(CCCCCC(N[C@@H](C(C)(C)C)C(N8[C@@H](C[C@@H](O)C8)C(N[C@H](C9=CC=C(C%10=C(N=CS%10)C)C=C9)C)=O)=O)=O)=O)CC7)C=C5)=O)=O)C=C4)CC3 |
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