DUB
Catalog No. | Inhibitor Name | DUB | USP/UBP | UCH | Other |
---|---|---|---|---|---|
A13190 | PR-619 | ** | *** | JOSD2,SENP6 core,DEN1 | |
A13277 | P5091 | ** | |||
A12715 | LDN-57444 | **** | |||
A13209 | IU1 | * | |||
A12933 | P22077 | * | |||
A14030 | ML323 | **** | |||
A15391 | b-AP15 | *** | |||
A10988 | Degrasyn | Bcr-Abl |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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DUBs-IN-2
Catalog No. A12842 -
DUBs-IN-1
Catalog No. A12827 -
b-AP15 (NSC 687852)
Catalog No. A15391 DUB 抑制剂b-AP15 (NSC 687852)是两种与蛋白酶体相关的DUBs的泛素特异性加工蛋白酶14(USP14)和泛素羧基末端水解酶同工酶L5(UCHL5)的抑制剂。 了解更多 -
Vialinin A
Catalog No. A15321 -
SJB2-043
Catalog No. A15238 -
ML-323
Catalog No. A14030 -
HBX 41108
Catalog No. A13352 -
P005091
Catalog No. A13277 -
LDN-57444
Catalog No. A12715 -
PR-619
Catalog No. A13190 -
WP1130 (Degrasyn)
Catalog No. A10988 DUB/Bcr/ABL 抑制剂WP1130 (Degrasyn)是一种新型的选择性小分子去泛素酶抑制剂和Bcr/Abl破坏途径激活剂,可特异性和快速下调野生型和突变型Bcr/Abl蛋白,而不会影响慢性粒细胞性白血病(CML)中的bcr/abl基因表达细胞。 了解更多