Duocarmycin

Name: Duocarmycin
SKU: A18472
Price: 2240 CNY
Rating: 5 (288 reviews)

目录号: A18472

Duocarmycin 依靠其特有的弯曲吲哚结构和一个螺环丙基环己二烯酮电亲体来发挥抗癌活性。Duocarmycin 是一种与 DNA 次要沟结合的烷化剂，并被探索用作药物-抗体偶联物（ADCs）。

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Grouped product items
规格	价格	库存
1mg	¥2,240.00	现货
5mg	¥3,640.00	现货
10mg	¥6,160.00	现货
25mg	¥12,740.00	现货
50mg	¥19,740.00	现货
100mg	¥33,740.00	现货
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Data Sheet

SDS

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生物活性

Discription

Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug?Cantibody conjugates (ADCs) .

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18472
分子式	C26H26ClN3O3
分子量	463.96
CAS号	1116745-06-2
SMILES	O=C(N1C[C@@H](CCl)C2=C1C=C(O)C3=CC=CC=C23)C(N4)=CC5=C4C=CC(OCCN(C)C)=C5
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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