DW14800

Name: DW14800
SKU: A18491
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A18491

PRMT5 inhibitor

DW14800 是一种蛋白质精氨酸甲基转移酶5（PRMT5）抑制剂，其半抑制浓度（IC50）为17纳摩尔。DW14800 降低了 H4R3me2s 的水平，并增强了 HNF4α 的转录，但不改变 PRMT5 的表达。具有抗癌活性。

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Grouped product items
规格	价格	库存
1mg	¥560.00	现货
2mg	¥875.00	现货
5mg	¥1,540.00	现货
10mg	¥2,730.00	现货
25mg	¥5,250.00	现货
50mg	¥6,930.00	现货
100mg	¥10,395.00	现货
*10mM 1mL in DMSO**	¥1,750.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18491
分子式	C31H36N4O3
分子量	512.64
CAS号	2243709-60-4
SMILES	CN(C)C1=CC=C(C(N2CCC(C=C(C(NCC(O)CN3CC(C=CC=C4)=C4CC3)=O)C=C5)=C5C2)=O)C=C1
其他名称	DW 14800, DW-14800
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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