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Dxd

目录号: A21517
DNA topoisomerase I 抑制剂
Dxd(用于ADC的Exatecan衍生物)是一种强效的DNA拓扑异构酶I抑制剂,具有0.31 μM的IC50,用作HER2靶向ADC(DS-8201a)的偶联药物。
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规格 价格 库存 数量
1mg
¥210.00
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5mg
¥420.00
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10mg
¥630.00
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25mg
¥1,050.00
现货
50mg
¥1,575.00
现货
100mg
¥2,905.00
现货
10mM * 1mL in DMSO
¥455.00
现货
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生物活性
Discription Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
Targets
Target Value
产品信息
目录号 A21517
分子式 C26H24FN3O6
分子量 493.48
CAS号 1599440-33-1
SMILES O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
其他名称 Exatecan derivative for ADC
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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