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E-64是一种不可逆的选择性半胱氨酸蛋白酶抑制剂，对木瓜蛋白酶的IC50为9 nM。
靶点信息
| Cysteine protease | ||||
| 9 nM |
| In vitro | DMSO | Warmed: 61 mg/mL (170.67 mM) | |
| Water | Warmed: 9 mg/mL (25.18 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.98 mL | 139.9 mL | 279.79 mL |
| 0.5 mM | 5.6 mL | 27.98 mL | 55.96 mL |
| 1 mM | 2.8 mL | 13.99 mL | 27.98 mL |
| 5 mM | 0.56 mL | 2.8 mL | 5.6 mL |
*The above data is based on the productmolecular weight 357.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13257 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 357.41 |
| Formula | C15H27N5O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 66701-25-5 |
| Synonyms | E64, E 64 |
| SMILES | CC(C)C[C@@H](C(=O)NCCCCN=C(N)N)NC(=O)[C@@H]1[C@H](O1)C(=O)O |
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