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E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.74 mL | 63.7 mL | 127.4 mL |
| 0.5 mM | 2.55 mL | 12.74 mL | 25.48 mL |
| 1 mM | 1.27 mL | 6.37 mL | 12.74 mL |
| 5 mM | 0.25 mL | 1.27 mL | 2.55 mL |
*The above data is based on the productmolecular weight 784.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19045 |
|---|---|
| M. Wt | 784.94 |
| Formula | C47H52N4O7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1073560-68-5 |
| SMILES | OC([C@@H](NC([C@H]1N(CCC1)C([C@H](C2CCCCC2)NC([C@@H](N(C(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C)C)=O)=O)=O)C(C6=CC=CC=C6)C7=CC=CC=C7)=O |
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