E7046

Name: E7046
SKU: A19711
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A19711

EP4 拮抗剂

E7046 是一种口服生物利用度高且特异性的 EP4 拮抗剂，具有 13.5 nM 的 IC50 和 23.14 nM 的 Ki，表现出抗肿瘤活性。

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规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥875.00	现货
50mg	¥1,540.00	现货
100mg	¥2,800.00	现货
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Data Sheet

SDS

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生物活性

Discription

E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19711
分子式	C22H18F5N3O4
分子量	483.39
CAS号	1369489-71-3
SMILES	O=C(O)C1=CC=C([C@@H](NC(C2=C(OC3=CC=CC(C(F)(F)F)=C3)N(C)N=C2C(F)F)=O)C)C=C1
其他名称	E-7046; E 7046
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (186.18 mM)
	Ethanol	<1 mg/mL
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.69 mL	103.44 mL	206.87 mL
0.5 mM	4.14 mL	20.69 mL	41.37 mL
1 mM	2.07 mL	10.34 mL	20.69 mL
5 mM	0.41 mL	2.07 mL	4.14 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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