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Stenoparib (E7449)

目录号: A21553
PARP1/PARP2 抑制剂
E7449 是一种强效的 PARP1PARP2 抑制剂,同时也能抑制 TNKS1TNKS2,其半抑制浓度(IC50)分别为 PARP1 2.0 nM、PARP2 1.0 nM、TNKS1TNKS2 约50 nM,使用的底物为 32P-NAD+
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
5mg
¥455.00
现货
10mg
¥805.00
现货
25mg
¥1,330.00
现货
50mg
¥2,030.00
现货
100mg
¥3,045.00
现货
200mg
¥4,550.00
现货
10mM * 1mL in DMSO
¥630.00
现货
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生物活性
Discription E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ?50 and ?50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A21553
分子式 C18H15N5O
分子量 317.34
CAS号 1140964-99-3
SMILES O=C1NNC2=C3C1=CC=CC3=NC(CN4CC5=C(C=CC=C5)C4)=N2
其他名称 E-7449, E 7449
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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