Ebselen
目录号: A20834
HIV-1 capsid CTD dimerization 抑制剂
Ebselen（SPI-1005）是一种抑制HIV-1衣壳CTD二聚化的抑制剂。Ebselen能够穿透血脑屏障，并抑制肌醇单磷酸酶（IMPase）。Ebselen是一种非毒性的硒有机药物，具有抗炎和抗氧化特性。Ebselen抑制QSOX1酶活性，并具有抗癌活性。
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生物活性
| Discription | Ebselen (SPI-1005) is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase (IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity . | |||||
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| Cell Research |
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产品信息
| 目录号 | A20834 |
|---|---|
| 分子式 | C13H9NOSe |
| 分子量 | 274.2 |
| CAS号 | 60940-34-3 |
| SMILES | O=C1N(C2=CC=CC=C2)[Se]C3=C1C=CC=C3 |
| 其他名称 | SPI1005, SPI 1005, SPI-1005, PZ-51, PZ 51, PZ51, CCG-39161, CCG39161, CCG 39161 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 52 mg/mL (189.65 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.47 mL | 182.35 mL | 364.7 mL |
| 0.5 mM | 7.29 mL | 36.47 mL | 72.94 mL |
| 1 mM | 3.65 mL | 18.23 mL | 36.47 mL |
| 5 mM | 0.73 mL | 3.65 mL | 7.29 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 Ebselen | Ebselen 供应商 | Ebselen 花费 | Ebselen 生产商 | 订购 Ebselen | Ebselen 代理商
| 购买 60940-34-3 | 60940-34-3 供应商 | 60940-34-3 花费 | 60940-34-3 生产商 | 订购 60940-34-3 | 60940-34-3 代理商