Elexacaftor

目录号: A20094
CFTR modulator
Elexacaftor(VX-445,Compound 1)是囊性纤维化跨膜传导调节因子(CFTR)的调节剂。
Grouped product items
规格 价格 库存 数量
1mg
¥560.00
现货
5mg
¥1,750.00
现货
10mg
¥2,835.00
现货
25mg
¥5,635.00
现货
50mg
¥7,875.00
现货
100mg
¥10,605.00
现货
10mM * 1mL in DMSO
¥2,310.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR).
产品信息
目录号 A20094
分子式 C26H34F3N7O4S
分子量 597.65
CAS号 2216712-66-0
SMILES CC1(C)C[C@H](C)CN1C2=C(C(NS(C3=CN(C)N=C3C)(=O)=O)=O)C=CC(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)=N2
其他名称 VX-445, VX445??
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 99 mg/mL (165.65 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.73 mL 83.66 mL 167.32 mL
0.5 mM 3.35 mL 16.73 mL 33.46 mL
1 mM 1.67 mL 8.37 mL 16.73 mL
5 mM 0.33 mL 1.67 mL 3.35 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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