Elobixibat
目录号: A20984
IBAT 抑制剂
Elobixibat 是一种强效的回肠胆酸转运蛋白(IBAT)抑制剂,其 IC50 值分别为 0.53 ± 0.17 nM、0.13 ± 0.03 nM 和 5.8 ± 1.6 nM,针对人类 IBAT、小鼠 IBAT 和犬类 IBAT。
Discription | Elobixibat is a potent ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.53 ?? 0.17 nM, 0.13 ?? 0.03 nM, and 5.8 ?? 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. |
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目录号 | A20984 |
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分子式 | C36H45N3O7S2 |
分子量 | 695.89 |
CAS号 | 439087-18-0 |
SMILES | O=C(O)CNC([C@@H](C1=CC=CC=C1)NC(COC2=C(SC)C=C(C3=C2)N(C4=CC=CC=C4)CC(CCCC)(CCCC)CS3(=O)=O)=O)=O |
其他名称 | A 3309, A3309, A-3309; AZD 7806, AZD7806, AZD-7806 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2