Elvitegravir (GS-9137) es un potente inhibidor del paso de transferencia de cadena de la integración mediada por la integrasa del virus de la inmunodeficiencia humana tipo 1 (VIH-1).
Lea El Khoury, .et al. , PeerJ Preprints, 2019, 7:e27833v1
El Khoury L, .et al. , Biochem Biophys Res Commun, 2017, Jul 1;488(3):433-438 PMID: 28478035
生物活性
Discription
Elvitegravir (GS-9137) is a potent inhibitor of the strand-transfer step of integration mediated by human immunodeficiency virus type 1 (HIV-1) integrase.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
溶解性数据
In vitro
DMSO
85 mg/mL (189.78 mM)
Water
Insoluble
Ethanol
33 mg/mL (73.67 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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