Tepotinib (EMD-1214063)

Name: Tepotinib (EMD-1214063)
SKU: A11257
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11257

c-Met 抑制剂

EMD-1214063 是一种 MET 酪氨酸激酶 抑制剂，具有潜在的抗肿瘤活性。它与 MET 酪氨酸激酶 结合并干扰 MET 信号传导途径，这可能诱导过度表达该激酶的肿瘤细胞凋亡。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥665.00	现货
10mg	¥1,050.00	现货
25mg	¥1,960.00	现货
50mg	¥2,765.00	现货
100mg	¥4,725.00	现货
500mg	¥10,115.00	现货
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Data Sheet

SDS

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生物活性

Discription

EMD-1214063 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. It binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11257
分子式	C29H28N6O2
分子量	492.6
CAS号	1100598-32-0
SMILES	CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC(=CC=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
其他名称	EMD1214063
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 4 mg/mL (8.12 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.3 mL	101.5 mL	203 mL
0.5 mM	4.06 mL	20.3 mL	40.6 mL
1 mM	2.03 mL	10.15 mL	20.3 mL
5 mM	0.41 mL	2.03 mL	4.06 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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