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EML 425是一种可逆且非竞争性的CBP/p300抑制剂，具有细胞渗透性（IC50值分别为1.1和2.9 uM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.7 mL | 113.51 mL | 227.01 mL |
| 0.5 mM | 4.54 mL | 22.7 mL | 45.4 mL |
| 1 mM | 2.27 mL | 11.35 mL | 22.7 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.54 mL |
*The above data is based on the productmolecular weight 440.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16180 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 440.5 |
| Formula | C27H24N2O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1675821-32-5 |
| Synonyms | EML-425, EML425 |
| SMILES | O=C1N(CC2=CC=CC=C2)C(/C(C(N1CC3=CC=CC=C3)=O)=C\C4=C(C)C=C(O)C=C4C)=O |
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