EN6

Name: EN6
SKU: A18524
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A18524

Autophagy activator

EN6 是一种新型共价自噬激活剂，它针对溶酶体 v-ATPase 的 ATP6V1A 亚基中的 半胱氨酸 277，通过 Rag 鸟苷三磷酸酶激活 mTORC1。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥525.00	现货
10mg	¥910.00	现货
25mg	¥1,470.00	现货
50mg	¥1,890.00	现货
100mg	¥2,905.00	现货
500mg	¥6,650.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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Data Sheet

SDS

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生物活性

Discription	EN6 is a novel covalent autophagy activator, targeting cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase, which activates mTORC1 via the Rag guanosine triphosphatases.

产品信息

目录号	A18524
分子式	C19H14F2N4O2
分子量	368.34
CAS号	1808714-73-9
SMILES	O=C(C1=CN(C2=CC=CC=C2F)N=C1)NC3=CC=C(F)C(NC(C=C)=O)=C3
其他名称	EN6; EN-6; EN 6
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	68 mg/mL (184.61 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.15 mL	135.74 mL	271.49 mL
0.5 mM	5.43 mL	27.15 mL	54.3 mL
1 mM	2.71 mL	13.57 mL	27.15 mL
5 mM	0.54 mL	2.71 mL	5.43 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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