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ENMD-2076 Tartrate

ENMD-2076 Tartrate

Name: ENMD-2076 Tartrate
SKU: A21583

目录号: A21583

multi-targeted kinase inhibitor

ENMD-2076 Tartrate Chemical Structure

CAS NO. 1291074-87-7

ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.

库存：现货

规格	价格	数量
5 mg	￥ 455.00
10 mg	￥ 784.00
50 mg	￥ 2,317.00
100 mg	￥ 4,634.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.

溶解度 *

In vitro (25°C)	DMSO	Warmed: 86 mg/mL (163.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.03 mL	95.14 mL	190.27 mL
0.5 mM	3.81 mL	19.03 mL	38.05 mL
1 mM	1.9 mL	9.51 mL	19.03 mL
5 mM	0.38 mL	1.9 mL	3.81 mL

*The above data is based on the productmolecular weight 525.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21583
作用机制	Inhibitor (抑制剂)
M. Wt	525.56
Formula	C25H31N7O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1291074-87-7
Synonyms	ENMD2076, ENMD 2076
SMILES	O[C@H](C(O)=O)[C@@H](C(O)=O)O.CC1=CC(NC2=NC(/C=C/C3=CC=CC=C3)=NC(N4CCN(CC4)C)=C2)=NN1