Entecavir
目录号: A17569
HBV 抑制剂
Entecavir（SQ 34676；BMS 200475）是一种强效且选择性的HBV抑制剂，在HepG2细胞中的EC50为3.75 nM。
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生物活性
| Discription | Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. |
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产品信息
| 目录号 | A17569 |
|---|---|
| 分子式 | C12H15N5O3 |
| 分子量 | 277.28 |
| CAS号 | 142217-69-4 |
| SMILES | O=C1NC(N)=NC2=C1N=CN2[C@@H]3C([C@H](CO)[C@@H](O)C3)=C |
| 其他名称 | BMS200475, BMS 200475, BMS-200475; SQ34676, SQ 34676, SQ-34676 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 48 mg/mL (173.11 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.06 mL | 180.32 mL | 360.65 mL |
| 0.5 mM | 7.21 mL | 36.06 mL | 72.13 mL |
| 1 mM | 3.61 mL | 18.03 mL | 36.06 mL |
| 5 mM | 0.72 mL | 3.61 mL | 7.21 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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