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Epacadostat (INCB024360)

Epacadostat (INCB024360)

Name: Epacadostat (INCB024360)
SKU: A15554

目录号: A15554

IDO 抑制剂

Product Citations (1)

Epacadostat (INCB024360) Chemical Structure

CAS NO. 1204669-58-8, 1204669-37-3

Epacadostat (INCB024360)是一种有效的选择性吲哚胺2,3-二加氧酶（IDO1）抑制剂，第2期的IC50为10 nM。

库存：现货

规格	价格	数量
5 mg	￥ 315.00
10 mg	￥ 539.00
25 mg	￥ 945.00

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Epacadostat (INCB024360)是一种有效的选择性吲哚胺2,3-二加氧酶（IDO1）抑制剂，第2期的IC50为10 nM。

靶点信息

IDO1
10 nM

溶解度 *

In vitro (25°C)	DMSO	74 mg/mL (168.86 mM)
	Water	Insoluble
	Ethanol	Warmed: 45 mg/mL
In vivo	5% DMSO+40% PEG 300+5% TWEEN 80+50 % ddH2O	4.13 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.82 mL	114.1 mL	228.19 mL
0.5 mM	4.56 mL	22.82 mL	45.64 mL
1 mM	2.28 mL	11.41 mL	22.82 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

*The above data is based on the productmolecular weight 438.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15554
作用机制	Inhibitor (抑制剂)
M. Wt	438.23
Formula	C11H13BrFN7O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1204669-58-8, 1204669-37-3
Synonyms	INCB 024360
SMILES	C1=CC(=C(C=C1NC(=C2C(=NON2)NCCNS(=O)(=O)N)N=O)Br)F