Epacadostat (INCB024360)

Name: Epacadostat (INCB024360)
SKU: A15554
Price: 210 CNY
Rating: 5 (3 reviews)

目录号: A15554

IDO 抑制剂

3 篇发表文献

Epacadostat 是一种强效且选择性的吲哚胺2,3-双加氧酶（IDO1）抑制剂，IC50 为 10 nM，处于第二阶段临床试验。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥560.00	现货
50mg	¥735.00	现货
100mg	¥1,330.00	现货
200mg	¥2,240.00	现货
500mg	¥3,815.00	现货
1g	¥5,530.00	现货
2g	¥7,595.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Epacadostat (INCB024360)发表的3篇文献

Chunbo He, .et al. , Cancer Discov, 2024, Jan 12;14(1):176-193 PMID: 37931287

Saeko Yoshioka, .et al. , Int J Tryptophan Res, 2022, Nov 30;15 PMID: 36467776

Marta Galan-Diez, .et al. , Cancer Discov, 2022, Apr 1;12(4):1106-1127 PMID: 35046097

生物活性

Discription

Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15554
分子式	C11H13BrFN7O4S
分子量	438.23
CAS号	1204669-58-8, 1204669-37-3
SMILES	C1=CC(=C(C=C1NC(=C2C(=NON2)NCCNS(=O)(=O)N)N=O)Br)F
其他名称	INCB 024360
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	74 mg/mL (168.86 mM)
	Water	Insoluble
	Ethanol	Warmed: 45 mg/mL
In vivo	5% DMSO+40% PEG 300+5% TWEEN 80+50 % ddH2O	4.13 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.82 mL	114.1 mL	228.19 mL
0.5 mM	4.56 mL	22.82 mL	45.64 mL
1 mM	2.28 mL	11.41 mL	22.82 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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