Epothilone A
目录号: A10359
Microtubule Associated 抑制剂
Epothilone A 通过在紫杉醇结合位点稳定微管形成,并在 G2/M 过渡期引起细胞周期阻滞,从而导致细胞毒性。
Discription | Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. | |||||
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Cell Research |
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目录号 | A10359 |
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分子式 | C26H39NO6S |
分子量 | 493.7 |
CAS号 | 152044-53-6 |
SMILES | C[C@H]1CCC[C@@H]2[C@@H](O2)C[C@H](OC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C |
其他名称 | EpoA |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 92 mg/mL (186.36 mM) | |
Water | Insoluble | ||
Ethanol | 92 mg/mL (186.36 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.26 mL | 101.28 mL | 202.55 mL |
0.5 mM | 4.05 mL | 20.26 mL | 40.51 mL |
1 mM | 2.03 mL | 10.13 mL | 20.26 mL |
5 mM | 0.41 mL | 2.03 mL | 4.05 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2