EPZ-5676 (Pinometostat)

Name: EPZ-5676 (Pinometostat)
SKU: A12735
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A12735

DOT1L 抑制剂

2 篇发表文献

EPZ-5676 是一种小分子抑制剂，针对组蛋白甲基转移酶，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥350.00	现货
10mg	¥525.00	现货
25mg	¥1,120.00	现货
50mg	¥1,960.00	现货
100mg	¥3,780.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用EPZ-5676 (Pinometostat)发表的2篇文献

Yoo H, .et al. , Cell Death Dis, 2020, Jan; 11(1): 14 PMID: 31908356

Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48

生物活性

Discription

EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A12735
分子式	C30H42N8O3
分子量	562.7
CAS号	1380288-87-8
SMILES	CC(C)N(C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C
其他名称	EPZ5676, EPZ 5676
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 88 mg/mL (156.38 mM)
	Water	Insoluble
	Ethanol	Warmed: 81 mg/mL (143.94 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.77 mL	88.86 mL	177.71 mL
0.5 mM	3.55 mL	17.77 mL	35.54 mL
1 mM	1.78 mL	8.89 mL	17.77 mL
5 mM	0.36 mL	1.78 mL	3.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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