EPZ020411 hydrochloride
目录号: A21802
PRMT6 inhibitor
EPZ020411 hydrochloride 是一种强效且选择性的 PRMT6 抑制剂,其 IC50 为 10 nM,对 PRMT6 相比 PRMT1 和 PRMT8 具有超过10倍的选择性。
Discription | EPZ020411 hydrochloride is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has ??10 fold selectivity for PRMT6 over PRMT1 and PRMT8. | ||
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Targets |
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目录号 | A21802 |
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分子式 | C25H39ClN4O3 |
分子量 | 479.06 |
CAS号 | 2070015-25-5 |
SMILES | CNCCN(C)CC1=CNN=C1C2=CC=C(O[C@H]3C[C@H](OCCC4CCOCC4)C3)C=C2.Cl[H] |
其他名称 | EPZ-020411, EPZ 020411 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 86 mg/mL (166.81 mM) | |
Water | 70 mg/mL (135.78 mM) | ||
Ethanol | 86 mg/mL (166.81 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.87 mL | 104.37 mL | 208.74 mL |
0.5 mM | 4.17 mL | 20.87 mL | 41.75 mL |
1 mM | 2.09 mL | 10.44 mL | 20.87 mL |
5 mM | 0.42 mL | 2.09 mL | 4.17 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2