Erdafitinib (JNJ-42756493)
目录号: A15957
FGFR 抑制剂
Erdafitinib 是一种强效且选择性的口服生物利用度高的全面成纤维细胞生长因子受体(FGFR)抑制剂,具有潜在的抗肿瘤活性。
Discription | Erdafitinib is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. | |||||
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Targets |
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Cell Research |
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目录号 | A15957 |
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分子式 | C25H30N6O2 |
分子量 | 446.55 |
CAS号 | 1346242-81-6 |
SMILES | CC(NCCN(C1=CC(OC)=CC(OC)=C1)C2=CC=C3N=CC(C4=CN(C)N=C4)=NC3=C2)C |
其他名称 | JNJ 42756493, JNJ42756493, JNJ-42756493 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 79 mg/mL (176.92 mM) | |
Water | Insoluble | ||
Ethanol | 79 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.39 mL | 111.97 mL | 223.94 mL |
0.5 mM | 4.48 mL | 22.39 mL | 44.79 mL |
1 mM | 2.24 mL | 11.2 mL | 22.39 mL |
5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2