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ERK-IN-1 (compound B) is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.29 mL | 86.44 mL | 172.88 mL |
| 0.5 mM | 3.46 mL | 17.29 mL | 34.58 mL |
| 1 mM | 1.73 mL | 8.64 mL | 17.29 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.46 mL |
*The above data is based on the productmolecular weight 578.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19080 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 578.42 |
| Formula | C26H27BrF3N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1715025-32-3 |
| SMILES | O=C(N[C@@H](C1=CC(F)=CC(Br)=C1)CNC)C2=CC=C(C3=NC([C@@H]4C[C@H](F)[C@@H](O)CC4)=CN=C3N)C=C2F |
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