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Erlotinib mesylate是人EGFR酪氨酸激酶的直接作用抑制剂，IC50为2 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.43 mL | 102.14 mL | 204.27 mL |
| 0.5 mM | 4.09 mL | 20.43 mL | 40.85 mL |
| 1 mM | 2.04 mL | 10.21 mL | 20.43 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.09 mL |
*The above data is based on the productmolecular weight 489.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15081 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 489.54 |
| Formula | C23H27N3O7S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 248594-19-6 |
| Synonyms | Tarceva, CP-358774, OSI-774, NSC 718781, R 1415 |
| SMILES | COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.CS(=O)(=O)O |
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