Esaxerenone

Name: Esaxerenone
SKU: A16925
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A16925

Aldosterone Receptor Ant激动剂

Esaxerenone，也被称为 CS-3150、XL-550，是一种非甾体抗矿物皮质激素药物，作为矿物皮质激素受体（MR）的高度选择性沉默拮抗剂，MR 是醛固酮的受体。Esaxerenone 对此受体的选择性超过其他类固醇激素受体1000倍以上，并且相对于现有的抗矿物皮质激素药物螺内酯和依普利酮，其对MR的亲和力分别高出4倍和76倍。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
2mg	¥630.00	现货
5mg	¥980.00	现货
10mg	¥1,610.00	现货
25mg	¥3,185.00	现货
50mg	¥5,110.00	现货
100mg	¥8,085.00	现货
500mg	¥16,205.00	现货
*10mM 1mL in DMSO**	¥1,085.00	现货
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Data Sheet

SDS

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生物活性

Discription

Esaxerenone, also known as CS-3150, XL-550, is a nonsteroidal antimineralocorticoid that acts as a highly selective silent antagonist of the mineralocorticoid receptor (MR), the receptor for aldosterone, with greater than 1,000-fold selectivity for this receptor over other steroid hormone receptors, and 4-fold and 76-fold higher affinity for the MR relative to the existing antimineralocorticoids spironolactone and eplerenone.

产品信息

目录号	A16925
分子式	C22H21F3N2O4S
分子量	466.47
CAS号	1632006-28-0
SMILES	CS(C1=CC=C(NC(C2=CN(CCO)C(C3=CC=CC=C3C(F)(F)F)=C2C)=O)C=C1)(=O)=O
其他名称	CS-3150, CS 3150, CS3150, XL-550, XL550, L 550
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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