Esaxerenone

目录号: A16925

Aldosterone Receptor 拮抗剂

Esaxerenone

Esaxerenone Chemical Structure

CAS NO. 1632006-28-0

Esaxerenone(CS-3150,XL-550)是一种非甾体类抗盐皮质激素,可作为盐皮质激素受体(MR)(醛固酮受体)的高度选择性沉默拮抗剂,对该受体的选择性是其他受体的1000倍以上类固醇激素受体,相对于现有的抗盐皮质激素螺内酯和依普利酮,与MR的亲和力分别高4倍和76倍。

库存: 现货

规格 价格 数量
1 mg
¥ 840.00
2 mg
¥ 1,540.00
5 mg
¥ 2,660.00
50 mg
¥ 11,760.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Esaxerenone(CS-3150,XL-550)是一种非甾体类抗盐皮质激素,可作为盐皮质激素受体(MR)(醛固酮受体)的高度选择性沉默拮抗剂,对该受体的选择性是其他受体的1000倍以上类固醇激素受体,相对于现有的抗盐皮质激素螺内酯和依普利酮,与MR的亲和力分别高4倍和76倍。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.44 mL 107.19 mL 214.38 mL
0.5 mM 4.29 mL 21.44 mL 42.88 mL
1 mM 2.14 mL 10.72 mL 21.44 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16925
作用机制 Antagonist (拮抗剂)
M. Wt 466.47
Formula C22H21F3N2O4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1632006-28-0
Synonyms CS-3150, CS 3150, CS3150, XL-550, XL550, L 550
SMILES CS(C1=CC=C(NC(C2=CN(CCO)C(C3=CC=CC=C3C(F)(F)F)=C2C)=O)C=C1)(=O)=O

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