ETC-1002
目录号: A15815
ACL 抑制剂 and AMPK activator
ETC-1002 是一种新型、首创、口服、每日一次的小分子 LDL-C 降低药物;它是肝脏 AMP 激活蛋白激酶(AMPK)的激活剂;同时具有强大的抑制肝脏 ATP-柠檬酸裂解酶(IC50=29 uM)的活性。
Discription | ETC-1002 is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM). | ||
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目录号 | A15815 |
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分子式 | C19H36O5 |
分子量 | 344.49 |
CAS号 | 738606-46-7 |
SMILES | CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O |
其他名称 | ESP-55016, ETC1002, ETC 1002 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 61 mg/mL (177.07 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.03 mL | 145.14 mL | 290.28 mL |
0.5 mM | 5.81 mL | 29.03 mL | 58.06 mL |
1 mM | 2.9 mL | 14.51 mL | 29.03 mL |
5 mM | 0.58 mL | 2.9 mL | 5.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2