Tinodasertib (ETC-206)
目录号: A19366
MNK1 and MNK2 inhibitor
ETC-206 是一种选择性的 MNK1 和 MNK2 抑制剂,其 IC50 分别为 64 nM 和 86 nM。
Discription | ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively. | |||||
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Targets |
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Cell Research |
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目录号 | A19366 |
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分子式 | C25H20N4O2 |
分子量 | 408.45 |
CAS号 | 1464151-33-4 |
SMILES | N#CC1=CC=C(C2=CN=C3C=CC(C4=CC=C(C(N5CCOCC5)=O)C=C4)=CN32)C=C1 |
其他名称 | ETC 206; ETC206 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 79 mg/mL (193.41 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.48 mL | 122.41 mL | 244.83 mL |
0.5 mM | 4.9 mL | 24.48 mL | 48.97 mL |
1 mM | 2.45 mL | 12.24 mL | 24.48 mL |
5 mM | 0.49 mL | 2.45 mL | 4.9 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2