ETP-46464

Name: ETP-46464
SKU: A13328

目录号: A13328

ATR 抑制剂

Product Citations (1)

ETP-46464 Chemical Structure

CAS NO. 1345675-02-6

ETP-46464是一种有效的选择性ATR抑制剂，IC50为25 nM。

库存：现货

规格	价格	数量
10 mg	￥ 980.00
25 mg	￥ 1,960.00
50 mg	￥ 3,500.00

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生物活性

ETP-46464是一种有效的选择性ATR抑制剂，IC50为25 nM。

靶点信息

mTOR	ATR	DNA-PK	PI3Kα	ATM
0.6 nM	14 nM	36 nM	170 nM	545 nM

溶解度 *

In vitro	DMSO	6 mg/mL (12.75 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.25 mL	106.27 mL	212.53 mL
0.5 mM	4.25 mL	21.25 mL	42.51 mL
1 mM	2.13 mL	10.63 mL	21.25 mL
5 mM	0.43 mL	2.13 mL	4.25 mL

*The above data is based on the productmolecular weight 470.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13328
作用机制	Inhibitor (抑制剂)
M. Wt	470.52
Formula	C30H22N4O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1345675-02-6
Synonyms	ETP46464, ETP 46464
SMILES	CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5