Exatecan

Name: Exatecan
SKU: A11231
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A11231

Topoisomerase I 抑制剂

Exatecan 通过稳定 topoisomerase I 和 DNA 之间的可切割复合物并抑制 DNA 断裂的再连接，抑制 topoisomerase I 活性，从而抑制 DNA 复制并触发凋亡细胞死亡。

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥175.00	现货
25mg	¥385.00	现货
50mg	¥595.00	现货
100mg	¥840.00	现货
500mg	¥2,310.00	现货
更大包装	更多折扣

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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Exatecan

Exatecan Mesylate

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生物活性

Discription

Exatecan inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.

Targets

Target	Value

产品信息

目录号	A11231
分子式	C24H22FN3O4
分子量	435.4554
CAS号	171335-80-1
SMILES	O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O
其他名称	DX 8951, DX8951
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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