Exemestane

Name: Exemestane
SKU: A10378

目录号: A10378

Aromatase 抑制剂

Exemestane Chemical Structure

CAS NO. 107868-30-4

Exemestane是一种口服类固醇芳香化酶抑制剂，除绝经后妇女的手术和/或放疗外，还用于ER阳性乳腺癌。

库存：现货

规格	价格	数量
10 mg	￥ 280.00
25 mg	￥ 490.00
50 mg	￥ 700.00
100 mg	￥ 840.00
10mM * 1mL in DMSO	￥ 350.00

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生物活性

Exemestane是一种口服类固醇芳香化酶抑制剂，除绝经后妇女的手术和/或放疗外，还用于ER阳性乳腺癌。

靶点信息

Aromatase (human)	Aromatase (rat)
30 nM	40 nM

溶解度 *

In vitro	DMSO	52 mg/mL (175.43 mM)
	Water	Insoluble
	Ethanol	15 mg/mL (50.6 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.74 mL	168.69 mL	337.38 mL
0.5 mM	6.75 mL	33.74 mL	67.48 mL
1 mM	3.37 mL	16.87 mL	33.74 mL
5 mM	0.67 mL	3.37 mL	6.75 mL

*The above data is based on the productmolecular weight 296.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10378
作用机制	Inhibitor (抑制剂)
M. Wt	296.4
Formula	C20H24O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	107868-30-4
Synonyms	Aromasin
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C