Exicorilant
目录号: A18620
Glucocorticoid receptor (GR) 拮抗剂
Exicorilant (CORT 125281) 是一种选择性的口服活性糖皮质激素受体(GR)拮抗剂,具有 7 nM 的 Ki 值。Exicorilant (CORT 125281) 有潜力克服肥胖、葡萄糖耐受不良和血脂异常。
Discription | Exicorilant (CORT 125281) is a selective and oral active glucocorticoid receptor (GR) antagonist, with a Ki value of 7 nM. Exicorilant (CORT 125281) has potential to overcome adiposity, glucose intolerance and dyslipidaemia. |
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目录号 | A18620 |
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分子式 | C26H23F4N7O3S |
分子量 | 589.15 |
CAS号 | 1781244-77-6 |
SMILES | O=C([C@]12CC3=C(N(C4=CC=C(F)C=C4)N=C3)C[C@]1([H])CCN(S(=O)(C5=NN(C)N=C5)=O)C2)C6=NC=CC(C(F)(F)F)=C6 |
其他名称 | Exicorilant; CORT125281; CORT-125281; CORT 125281; |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2